Description

(6R)-7β-[[(S)-(Aminocarbonyl)AminoAcetyl]Amino]-7α-Methoxy-3-[(1-Methyl-1H-Tetrazol-5-Yl)Thiomethyl]Cepham-3-Ene-4-Carboxylic Acid is a key advanced pharmaceutical intermediate in the synthesis of potent third-generation cephalosporin antibiotics. This compound matters for its critical role in constructing the core structure of cephamycin-class drugs, which are valued for their broad-spectrum antibacterial activity and stability against β-lactamases. Pharmaceutical manufacturers and fine chemical suppliers require this high-purity intermediate to ensure the efficacy and quality of the final active pharmaceutical ingredient (API).

Application

• Primary Intermediate in the synthesis of Cefmetazole and related cephamycin antibiotics.
• Research & Development for novel β-lactam antibiotics and studying structure-activity relationships (SAR).
• Pharmaceutical Manufacturing for producing finished dosage forms of injectable antibiotics.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Process Chemistry for scaling up and optimizing antibiotic production pathways.

Basic Information

Product Name	(6R)-7β-[[(S)-(Aminocarbonyl)AminoAcetyl]Amino]-7α-Methoxy-3-[(1-Methyl-1H-Tetrazol-5-Yl)Thiomethyl]Cepham-3-Ene-4-Carboxylic Acid
CAS No.	65700-47-2
Molecular Formula	C20H22N8O6S2
Molecular Weight	534.57 g/mol
Synonyms	7β-[(S)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid (Cefmetazole intermediate); Cefmetazole Acid; (6R,7R)-7-[[(2S)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino]-7-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefmetazole Side Chain Acid; 7-ACA derivative for Cefmetazole; Cefmetazole Nucleus
EINECS	Contact for details

Quality Control

Our (6R)-7β-[[(S)-(Aminocarbonyl)AminoAcetyl]Amino]-7α-Methoxy-3-[(1-Methyl-1H-Tetrazol-5-Yl)Thiomethyl]Cepham-3-Ene-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened under conditions of low humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.