Description

2,2,2-Trifluoro-n-Methyl-1-Phenylethanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a phenyl ring and a trifluoroethylamine moiety, which can impart desirable properties like metabolic stability and altered lipophilicity to target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers or advanced organic materials that require fluorinated components.
• Chemical Biology Probes: Useful for creating molecular probes to study enzyme function or biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical building block for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2,2,2-Trifluoro-n-Methyl-1-Phenylethanamine
CAS No.	65687-09-4
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	N-Methyl-2,2,2-trifluoro-1-phenylethanamine; α-(Trifluoromethyl)benzylmethylamine; 1-Phenyl-2,2,2-trifluoro-N-methylethanamine; N-Methyl-α-(trifluoromethyl)benzylamine; 2,2,2-Trifluoro-1-phenylethanamine, N-methyl-; (RS)-N-Methyl-1-phenyl-2,2,2-trifluoroethylamine; 65687-09-4; Benzylamine, α-(trifluoromethyl)-N-methyl-
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-Methyl-1-Phenylethanamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.