Description

Benzenemethanamine, .Alpha.,3-Bis(Trifluoromethyl)- is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of a reactive benzylic amine group and electron-withdrawing trifluoromethyl substituents, which impart distinct physicochemical properties to target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by material scientists exploring advanced polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those requiring enhanced metabolic stability, lipophilicity, or bioavailability.
• Agrochemical Active Ingredient Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group is a critical pharmacophore.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and liquid crystalline materials with tailored properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral or fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and novel fluorination reactions in academic and industrial R&D settings.

Basic Information

Product Name	Benzenemethanamine, .Alpha.,3-Bis(Trifluoromethyl)-
CAS No.	65686-68-2
Molecular Formula	C10H7F6N
Molecular Weight	255.16 g/mol
Synonyms	α,3-Bis(trifluoromethyl)benzylamine; 1-[3,5-Bis(trifluoromethyl)phenyl]methanamine; 3,5-Bis(trifluoromethyl)benzylamine; (3,5-Bis(trifluoromethyl)phenyl)methanamine; 3,5-Bis(trifluoromethyl)benzenemethanamine; 3,5-Bis(trifluoromethyl)phenylmethylamine; 3,5-Di(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Our Benzenemethanamine, .Alpha.,3-Bis(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.