Description

Boc-Lys(Me)2-Oh is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group and dimethylated lysine side chain. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of modified lysine residues. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Peptide Synthesis: A key intermediate for the incorporation of dimethyl-lysine analogs into custom peptide sequences.
• Pharmaceutical Research: Used in the development of peptide drugs targeting epigenetic regulation, as dimethylated lysine mimics specific post-translational modifications.
• Bioconjugation: Serves as a precursor for creating functionalized linkers or tags in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: Employed in the synthesis of probes and inhibitors for studying protein-protein interactions and enzyme function.
• Process Development: Used in scaling up the production of therapeutic peptides under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	Boc-Lys(Me)2-Oh
CAS No.	65671-53-6
Molecular Formula	C₁₄H₂₈N₂O₄
Molecular Weight	288.39 g/mol
Synonyms	N(ε),N(ε)-Dimethyl-N(α)-Boc-L-lysine; N(α)-Boc-N(ε),N(ε)-dimethyl-L-lysine; Boc-N(ε),N(ε)-dimethyl-L-lysine; (2S)-6-(Dimethylamino)-2-{[(2-methylpropan-2-yl)oxy]carbonylamino}hexanoic acid; Boc-Lys(Me2)-OH; Boc-Dimethyllysine-OH; N(α)-tert-Butoxycarbonyl-N(ε),N(ε)-dimethyl-L-lysine
EINECS	Contact for details

Quality Control

Our Boc-Lys(Me)2-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical data including HPLC purity, chiral purity, and NMR confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.