Description

(S)-2-Hydroxy-n-Methyl-2-Phenylacetamide is a chiral intermediate of significant importance in the synthesis of optically active pharmaceutical compounds. Its value lies in its role as a key building block for active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs. This product is essential for research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in advanced organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the production of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in the synthesis of complex molecules requiring high stereochemical control.
• Research & Development: Serves as a valuable standard and starting material in medicinal chemistry and process research laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where specific chirality is required for functionality.

Basic Information

Product Name	(S)-2-Hydroxy-n-Methyl-2-Phenylacetamide
CAS No.	65645-88-7
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(S)-Mandelamide, N-Methyl; (S)-2-Hydroxy-2-phenyl-N-methylacetamide; (S)-α-Hydroxy-N-methylbenzeneacetamide; L-N-Methylmandelamide; (S)-(-)-N-Methylmandelamide; (2S)-2-Hydroxy-2-phenyl-N-methylacetamide; N-Methyl-(S)-mandelamide
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxy-n-Methyl-2-Phenylacetamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and chiral integrity, meeting the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.