Description

Asenapine CAS NO 65576-45-6 is a high-purity atypical antipsychotic compound. It is a critical active pharmaceutical ingredient (API) valued for its specific receptor binding profile. This product is essential for pharmaceutical manufacturers and research institutions developing treatments for psychiatric and neurological disorders.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of antipsychotic medications.
• Neurological Research: A key compound in preclinical and clinical studies investigating mechanisms of action for schizophrenia and bipolar disorder.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Drug Development: Used in the R&D of novel dosage forms, including sublingual tablets and other delivery systems.
• Metabolite Synthesis: Acts as a precursor or reference point in the synthesis and study of its metabolic derivatives.

Basic Information

Product Name	Asenapine
CAS No.	65576-45-6
Molecular Formula	C17H16ClNO
Molecular Weight	285.77 g/mol
Synonyms	trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole; (3aRS,12bRS)-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole; Org 5222; SCH 900222; Sycrest (trade name); Saphris (trade name)
EINECS	Contact for details

Quality Control

Our Asenapine is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by validated methods (e.g., HPLC, IR) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.