Description

Cefuroxime Lysine CAS NO 65527-51-7 is a lysine salt derivative of the second-generation cephalosporin antibiotic, cefuroxime. This formulation is critical for enhancing the stability and solubility of the active pharmaceutical ingredient, making it suitable for advanced parenteral drug formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of sterile injectable antibiotics to combat a broad spectrum of bacterial infections.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of sterile injectable antibiotic formulations.
• Key intermediate in the synthesis of more complex cephalosporin-based pharmaceutical products.
• Reference standard in analytical laboratories for quality control and method development (HPLC, spectroscopy).
• Research and development of novel antibiotic delivery systems and combination therapies.
• Production of lyophilized (freeze-dried) powder for reconstitution in hospital and clinical settings.

Basic Information

Product Name	Cefuroxime Lysine
CAS No.	65527-51-7
Molecular Formula	C20H30N6O10S2
Molecular Weight	578.62 g/mol
Synonyms	Cefuroxime Lysinate; (6R,7R)-3-[(Carbamoyloxy)methyl]-7-[[(Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid lysine salt; Cefuroxime L-Lysine Salt; Zinacef Lysine Salt; Cefuroxime Mono-L-Lysinate; (6R,7R)-7-[2-(2-Furyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid lysine salt
EINECS	Contact for details

Quality Control

Our Cefuroxime Lysine is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (1% Solution)	5.0 - 7.0
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.