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Technetium Tc 99M Dimercaptosuccinic Acid CAS NO 65438-08-6


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CAS No.:65438-08-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Technetium Tc 99M Dimercaptosuccinic Acid is a diagnostic radiopharmaceutical agent used in nuclear medicine imaging. This compound is critical for the functional assessment of the renal cortex, providing high-resolution images for accurate medical diagnosis. It is primarily utilized by radiopharmacies, hospitals, and diagnostic imaging centers for renal scintigraphy procedures. The agent is prepared by complexing the radioactive isotope Technetium-99m with the chelating ligand dimercaptosuccinic acid.

Application

  • Renal Cortical Imaging: The primary application for the detection of renal parenchymal abnormalities, including scars from pyelonephritis.
  • Differential Renal Function Assessment: Used to quantify the relative function of each kidney, essential for pre- and post-surgical evaluation.
  • Evaluation of Renal Masses: Helps in characterizing space-occupying lesions within the kidney.
  • Pediatric Urology: Particularly valuable in children for diagnosing congenital anomalies and vesicoureteral reflux consequences.
  • Monitoring Transplanted Kidneys: Assists in the post-operative monitoring of kidney graft function and viability.

Basic Information

Product Name Technetium Tc 99M Dimercaptosuccinic Acid
CAS No. 65438-08-6
Molecular Formula C4H7O4S2 • 99mTc
Molecular Weight Contact for details
Synonyms Technetium-99m DMSA; 99mTc-DMSA; Tc-99m Succimer; DMSA Scan Agent; Renal Scan Agent; Dimercaptosuccinic Acid Tc 99m; Technetium (99mTc) Dimercaptosuccinate; V-40 DMSA Kit
EINECS Contact for details

Quality Control

Our Technetium Tc 99M Dimercaptosuccinic Acid is manufactured under strict quality systems. Each batch is tested to ensure it meets stringent specifications for radiochemical purity, pH, sterility, and apyrogenicity, adhering to relevant pharmacopoeial standards (e.g., USP, Ph. Eur.). A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store the lyophilized kit at 2-8°C. After reconstitution with sterile Sodium Pertechnetate Tc 99m Injection, the prepared radiopharmaceutical should be used within the time frame specified in the kit instructions. Due to its hygroscopic nature, protect the kit from moisture.

Specification

Item Specification
Appearance White to off-white lyophilized powder
pH (after reconstitution) 2.5 - 3.5
Radiochemical Purity (HPLC/TLC) ≥ 90%
Sterility Test Sterile
Bacterial Endotoxins < 175 EU/Vial
Identification (IR) Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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