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(R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro(1,1'Binaphthalene)-2,2'-Diol CAS NO 65355-08-0
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CAS No.:65355-08-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro(1,1'Binaphthalene)-2,2'-Diol CAS NO 65355-08-0 is a high-purity, chiral binaphthol derivative, a crucial building block in asymmetric synthesis. Its value lies in its role as a versatile ligand and catalyst precursor for creating enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high stereoselectivity in their synthetic processes.
Application
- Asymmetric Catalysis: Serves as a privileged chiral ligand for transition metal-catalyzed reactions, including cross-couplings, hydrogenations, and oxidations.
- Pharmaceutical Intermediate Synthesis: Key precursor in the production of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and more.
- Agrochemical Development: Used in the synthesis of chiral herbicides, fungicides, and pesticides where specific stereochemistry is critical for bioactivity and environmental safety.
- Material Science Research: Employed in the development of chiral polymers, liquid crystals, and molecular recognition systems.
- Academic & Industrial R&D: A fundamental tool for chemists exploring new methodologies in stereoselective synthesis and organocatalysis.
Basic Information
| Product Name | (R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro(1,1'Binaphthalene)-2,2'-Diol |
| CAS No. | 65355-08-0 |
| Molecular Formula | C₂₀H₂₀Br₂O₂ |
| Molecular Weight | 452.18 g/mol |
| Synonyms | (R)-(+)-3,3'-Dibromo-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Dibromo-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Dibromo-BINOL; (R)-3,3'-Dibromo-1,1'-bi-2-naphthol; (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol; (R)-H8-3,3'-Dibromo-BINOL; (R)-Octahydro-3,3'-dibromo-BINOL |
| EINECS | Contact for details |
Quality Control
Every batch of our (R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro(1,1'Binaphthalene)-2,2'-Diol undergoes rigorous analytical testing to ensure exceptional chemical purity and enantiomeric excess (ee). Our quality protocols are designed to meet the stringent requirements of advanced R&D and cGMP manufacturing environments. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (HPLC), and identity confirmation is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Heavy Metals | < 20 ppm |
| Residue on Ignition | < 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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