Description

3-Butyn-2-Ol is a versatile organic compound featuring both a hydroxyl group and a terminal alkyne functionality, making it a valuable building block in synthetic organic chemistry. This bifunctional nature allows it to serve as a key intermediate in the creation of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as click chemistry, Sonogashira couplings, and the synthesis of heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring alkyne motifs for further derivatization.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its alkyne group enables specific molecular modifications.
• Click Chemistry Reagent: Serves as a fundamental component in Huisgen cycloaddition (copper-catalyzed azide-alkyne cycloaddition) reactions for bioconjugation, polymer science, and material surface functionalization.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties, such as conductive polymers or advanced resins.
• Organic Synthesis Building Block: Employed in Sonogashira, Glaser, and other palladium-catalyzed coupling reactions to construct complex organic molecules for research and industrial applications.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	3-Butyn-2-Ol
CAS No.	65337-13-5
Molecular Formula	C₄H₆O
Molecular Weight	70.09 g/mol
Synonyms	3-Butyn-2-ol; 2-Butyn-4-ol; 3-Butyn-2-ol (principal name); 1-Methyl-2-propyn-1-ol; 2-Propyn-1-ol, 1-methyl-; But-3-yn-2-ol; Methyl ethynyl carbinol
EINECS	Contact for details

Quality Control

Our 3-Butyn-2-Ol is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile nature, keep container tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	0.890 - 0.910
Refractive Index (20°C)	1.420 - 1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.