Description

Metallothionein Ii From Rabbit Liver CAS NO 65278-41-3 is a purified, low molecular weight protein rich in cysteine residues, enabling it to bind heavy metals with high affinity. This compound is a critical research tool for studying cellular metal homeostasis, detoxification pathways, and oxidative stress responses. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, molecular biology, and pharmaceutical development for applications ranging from biomarker studies to the development of chelation therapies.

Application

• Biochemical Research: Used as a standard or reagent in studies of metal-binding proteins, metalloprotein structure-function, and gene expression regulation.
• Toxicology Studies: Serves as a key biomarker and experimental tool for investigating heavy metal (e.g., cadmium, zinc, copper) detoxification mechanisms in biological systems.
• Oxidative Stress Research: Employed in assays to understand the role of metallothioneins in scavenging free radicals and protecting against oxidative damage.
• Pharmaceutical Development: Investigated for potential therapeutic applications in conditions related to metal overload or deficiency, and in neuroprotection research.
• Diagnostic Kit Manufacturing: May be used as a purified component in the development of immunoassays or test kits for research purposes.
• Cell Culture & In Vitro Studies: Applied in controlled experiments to modulate intracellular metal concentrations and study subsequent cellular responses.

Basic Information

Product Name	Metallothionein Ii From Rabbit Liver
CAS No.	65278-41-3
Molecular Formula	Contact for details
Molecular Weight	~6-7 kDa (Approximate, varies by isoform)
Synonyms	Metallothionein-2; MT-II; MT2; Rabbit Liver Metallothionein II; Metallothionein Isoform II; Cadmium-Binding Protein; Zinc-Binding Protein; Low Molecular Weight Metal-Binding Protein
EINECS	Contact for details

Quality Control

Our Metallothionein Ii From Rabbit Liver is produced and handled under controlled conditions to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes rigorous analytical testing. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as purity, identity, and biological activity. We adhere to stringent in-house quality standards suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (SDS-PAGE)	≥ 90%
Protein Content (Bradford)	≥ 95% of dry weight
Metal Content (AAS/ICP)	Zinc and/or Cadmium content as specified
Biological Activity	Metal-binding capacity confirmed
Endotoxin Level	< 1.0 EU/mg (if applicable)
Solubility	Soluble in aqueous buffers, dilute acids

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.