Description

Ac-D-Tyr-OMe is a protected derivative of the D-isomer of the amino acid tyrosine, specifically N-acetyl-D-tyrosine methyl ester. This chiral building block is essential for the synthesis of peptides and peptidomimetics with specific stereochemistry, ensuring high biological activity and stability. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity, enantiomerically pure components for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of therapeutic peptides, enzyme inhibitors, and receptor agonists/antagonists.
• Biochemical Research: Used in proteomics, enzyme-substrate studies, and as a standard in analytical method development for amino acid and peptide analysis.
• Peptide Synthesis (SPPS & Solution Phase): Serves as a protected D-tyrosine residue in solid-phase and solution-phase peptide synthesis to construct complex peptide sequences.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in the synthesis of non-natural amino acids and other chiral compounds.
• Material Science: Potential use in developing specialized polymers, coatings, or biomaterials that incorporate amino acid-based motifs for specific functional properties.

Basic Information

Product Name	Ac-D-Tyr-OMe
CAS No.	65160-71-6
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25 g/mol
Synonyms	N-Acetyl-D-tyrosine methyl ester; Methyl N-acetyl-D-tyrosinate; D-Tyrosine, N-acetyl-, methyl ester; Ac-D-Tyr-OMe; (R)-Methyl 2-acetamido-3-(4-hydroxyphenyl)propanoate; N-Acetyl-O-methyl-D-tyrosine; Ac-D-Tyr-Me; N-Acetyl-D-tyrosine methyl ester
EINECS	Contact for details

Quality Control

Every batch of Ac-D-Tyr-OMe is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles by HPLC is available for each lot, supporting compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.