Description

25-Desacetylrifampin Quinone is a key chemical intermediate and reference standard derived from the rifamycin antibiotic family. This compound is of significant importance in pharmaceutical research and development, particularly for the synthesis and quality control of advanced antibacterial agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in antibiotic development and impurity profiling.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel rifamycin derivatives and related antibacterial compounds.
• Reference Standard: Used as a high-purity standard in analytical methods (HPLC, LC-MS) for the identification and quantification of impurities in rifampin and related drug substances.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) and metabolic pathways of rifamycin-class antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and process development for new antibacterial APIs.
• Quality Control & Assurance: Essential for pharmaceutical QC laboratories to monitor degradation products and ensure batch-to-batch consistency of rifampin-based medications.

Basic Information

Product Name	25-Desacetylrifampin Quinone
CAS No.	65110-92-1
Molecular Formula	C42H56N4O12
Molecular Weight	808.92 g/mol
Synonyms	25-Desacetylrifampicin Quinone; 25-Deacetylrifampin Quinone; 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin SV Quinone; Rifampin Quinone Metabolite; 25-Desacetylrifampin Quinone; 25-Deacetylrifampicin Quinone; 25-O-Desacetylrifampin Quinone
EINECS	Contact for details

Quality Control

Our 25-Desacetylrifampin Quinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for use as a reference standard and pharmaceutical intermediate. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider under an inert atmosphere. Keep container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Reddish-brown to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.