Description

3-Cyanothioanisole is a versatile aromatic nitrile and thioether compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of a cyano group and a thioanisole moiety, enabling the construction of complex heterocyclic systems and functionalized aromatic targets. This high-purity building block is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, facilitating the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bioactive molecules, including kinase inhibitors and other heterocyclic APIs.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to prepare specialized ligands for transition metal catalysis and asymmetric synthesis.
• Material Science Research: Monomer or intermediate for developing advanced polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Intermediate in the production of specialized dyes and functional colorants.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations and fine chemical custom synthesis.

Basic Information

Product Name	3-Cyanothioanisole
CAS No.	65052-48-4
Molecular Formula	C8H7NS
Molecular Weight	149.21 g/mol
Synonyms	3-(Methylthio)benzonitrile; 3-Methylthiobenzonitrile; m-(Methylthio)benzonitrile; Benzonitrile, 3-(methylthio)-; 3-Thioanisyl cyanide; 3-Cyanophenyl methyl sulfide; 3-Methanesulfinylbenzonitrile (related); 65052-48-4
EINECS	Contact for details

Quality Control

Our 3-Cyanothioanisole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.