Description

Benzamide, n-Methyl-4-(Trifluoromethyl)- CAS NO 65017-76-7 is a specialized trifluoromethylated benzamide derivative, a high-value intermediate in advanced organic synthesis. Its molecular structure, featuring both an amide linkage and a robust trifluoromethyl group, makes it a critical building block for creating compounds with enhanced metabolic stability and lipophilicity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the exploration of novel chemical spaces in medicinal and synthetic chemistry.
• Fluorine Chemistry Building Block: An important reagent for introducing the trifluoromethyl moiety into more complex molecular architectures, leveraging its unique electronic and steric properties.

Basic Information

Product Name	Benzamide, n-Methyl-4-(Trifluoromethyl)-
CAS No.	65017-76-7
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	N-Methyl-4-(trifluoromethyl)benzamide; 4-(Trifluoromethyl)-N-methylbenzamide; N-Methyl-alpha,alpha,α-trifluoro-p-toluamide; 4-(Trifluoromethyl)benzoic acid methylamide; p-(Trifluoromethyl)-N-methylbenzamide; Methyl(4-trifluoromethylbenzoyl)amine; Benzamide, N-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our Benzamide, n-Methyl-4-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.