Description

Halofuginone Hydrobromide is a synthetic quinazolinone derivative and a halogenated alkaloid salt, widely recognized for its potent antiprotozoal and anti-fibrotic properties. This compound is critical for developing therapeutic and preventative solutions in veterinary medicine and biomedical research. It is primarily utilized by manufacturers in the animal health sector and research institutions focused on parasitic diseases and tissue fibrosis.

Application

• Veterinary Coccidiostat: A key active ingredient in feed additives and premixes for the prevention and control of coccidiosis in poultry (broilers, layers) and other livestock.
• Anti-Fibrotic Research: Serves as a potent inhibitor of collagen synthesis (Type I) in preclinical studies for fibrotic diseases such as scleroderma, liver cirrhosis, and keloid scarring.
• Pharmaceutical Intermediates: Used in the synthesis of more complex therapeutic agents targeting parasitic infections.
• Veterinary Medicinal Products: Formulated into oral solutions, tablets, or injectables for targeted treatment protocols in companion and farm animals.
• Biochemical Research: Employed as a selective probe to study TGF-β signaling pathways and the mechanisms of extracellular matrix deposition.
• Feed Grade Applications: Incorporated into medicated feeds under strict regulatory guidelines to ensure animal health and food safety.

Basic Information

Product Name	Halofuginone Hydrobromide
CAS No.	64924-67-0
Molecular Formula	C16H17Br2N3O3 • HBr
Molecular Weight	495.05 g/mol (as hydrobromide salt)
Synonyms	Halofuginone HBr; 7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone hydrobromide; Stenorol; RU-19110 hydrobromide; Febrifugine derivative hydrobromide
EINECS	Contact for details

Quality Control

Our Halofuginone Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identification by IR and MS, to ensure it meets high-purity standards suitable for veterinary and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.