Description

7β,25-Dihydroxycholesterol is a specific oxysterol metabolite of cholesterol, playing a significant role in the regulation of immune and inflammatory responses. This compound is a critical reference standard and research biochemical for studying lipid signaling pathways, particularly those involving the liver X receptor (LXR). It is essential for pharmaceutical R&D, academic research, and diagnostic development in areas such as immunology, metabolic disease, and cancer biology.

Application

• Biomedical Research: Used as a high-purity reference standard in studies of cholesterol metabolism and oxysterol biology.
• Drug Discovery: Serves as a key intermediate or biological probe in pharmaceutical development targeting LXR pathways for treating atherosclerosis and inflammatory diseases.
• Diagnostic Development: Employed in the calibration and development of assays (e.g., LC-MS/MS) for quantifying oxysterols in clinical and research samples.
• Cell Signaling Studies: Utilized to investigate the role of specific oxysterols in immune cell function and inflammation regulation.
• Academic Research: A vital tool for universities and research institutes exploring lipidomics, biochemistry, and molecular biology.
• Biochemical Production: Acts as a precursor or standard in the synthesis of more complex steroidal compounds or labeled analogs.

Basic Information

Product Name	7β,25-Dihydroxycholesterol
CAS No.	64907-21-7
Molecular Formula	C27H46O3
Molecular Weight	418.66 g/mol
Synonyms	(25R)-7β,26-Dihydroxycholesterol; 7β,25-Dihydroxycholest-5-en-3β-ol; 5-Cholestene-3β,7β,25-triol; 7β-Hydroxy-25-hydroxycholesterol; 25-Hydroxy-7β-hydroxycholesterol; Oxysterol 7β,25-diOHC
EINECS	Contact for details

Quality Control

Our 7β,25-Dihydroxycholesterol is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.