Description

Pirbuterol-D9 Dihydrochloride is a high-purity, deuterium-labeled internal standard essential for precise quantitative analysis in bioanalytical and pharmaceutical research. This stable isotope-labeled compound is critical for ensuring analytical accuracy and reliability in method development and validation. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, contract research organization (CRO), and clinical diagnostics sectors for advanced mass spectrometry applications.

Application

• Internal Standard for LC-MS/MS: Serves as a critical deuterated internal standard for the accurate quantification of Pirbuterol and related compounds in complex biological matrices such as plasma, serum, and urine.
• Pharmaceutical R&D: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies, metabolism investigations, and bioequivalence testing during drug development.
• Clinical Research & Diagnostics: Enables precise measurement of drug concentrations in patient samples for therapeutic drug monitoring (TDM) and clinical trial analysis.
• Forensic & Anti-Doping Analysis: Applied in confirmatory testing for prohibited substances in forensic toxicology and sports anti-doping programs.
• Method Development & Validation: A key reagent for developing, optimizing, and validating robust, sensitive, and selective analytical methods according to FDA, EMA, and ICH guidelines.
• Reference Material Production: Used in the preparation of certified reference materials (CRMs) and quality control (QC) samples to ensure data integrity across laboratories.

Basic Information

Product Name	Pirbuterol-D9 Dihydrochloride
CAS No.	64856-15-1
Molecular Formula	C12H11D9Cl2N2O3
Molecular Weight	326.24 g/mol (for deuterated form)
Synonyms	Pirbuterol-d9 Dihydrochloride; 2-tert-Butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)ethanol-d9 Dihydrochloride; (±)-Pirbuterol-d9 Dihydrochloride; 5-(2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl)-6-hydroxy-3-pyridinemethanol-d9 Dihydrochloride; 8-Hydroxy-5-[(1-hydroxy-2-tert-butylamino)ethyl]carbostyril-d9 Dihydrochloride; Exirel-d9 Dihydrochloride; CP-24314-1-d9
EINECS	Contact for details

Quality Control

Our Pirbuterol-D9 Dihydrochloride is manufactured under strict quality systems to ensure the high purity and isotopic enrichment required for sensitive analytical applications. Each batch undergoes comprehensive testing, including assay by HPLC, determination of isotopic purity by mass spectrometry, and confirmation of chemical structure. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications and traceability to relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccant conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.