Description

Monodecarboxy Piperacilloic Acid is a key pharmaceutical intermediate and a crucial metabolite in the study of β-lactam antibiotics. This compound is essential for research and development in the synthesis and metabolic profiling of advanced penicillin derivatives. It is primarily utilized by pharmaceutical R&D laboratories, analytical service providers, and manufacturers of active pharmaceutical ingredients (APIs) for quality control and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis and research of piperacillin and related β-lactam antibiotic compounds.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and metabolic studies to identify and quantify drug metabolites.
• Quality Control & Impurity Profiling: Employed in HPLC and LC-MS methods for the identification and control of related substances in bulk API and finished drug products.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to β-lactamase activity and antibiotic resistance mechanisms.
• Process Development: Used in the optimization of fermentation and synthetic routes for the production of semi-synthetic penicillins.

Basic Information

Product Name	Monodecarboxy Piperacilloic Acid
CAS No.	64817-23-8
Molecular Formula	C23H27N5O7S
Molecular Weight	517.56 g/mol
Synonyms	3-Carboxy-3-(piperazin-1-ylmethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Piperacilloic Acid Metabolite; Desmethylpiperacillin; (2S,5R,6R)-3,3-Dimethyl-6-[(R)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetamido]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid derivative; PCA; Monodescarboxypiperacillin acid.
EINECS	Contact for details

Quality Control

Our Monodecarboxy Piperacilloic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.