Description

Piperacilloic Acid is a key pharmaceutical intermediate and a vital metabolite of the broad-spectrum antibiotic piperacillin. Its primary commercial value lies in its role in the synthesis, quality control, and metabolic studies of β-lactam antibiotics. This compound is essential for manufacturers and research institutions in the pharmaceutical and fine chemical sectors focused on antibiotic development and analytical standards.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of piperacillin and related β-lactam antibiotics.
• Analytical Reference Standard: Used in HPLC, LC-MS, and other chromatographic methods for quality control and assay validation of piperacillin API and formulations.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the behavior of piperacillin in biological systems.
• Impurity Standard: Serves as a certified reference material for identifying and quantifying related substances in compliance with pharmacopeial guidelines (USP, EP).
• Research & Development: Utilized in medicinal chemistry for the development of new antibiotic derivatives and resistance studies.

Basic Information

Product Name	Piperacilloic Acid
CAS No.	64817-22-7
Molecular Formula	C23H27N5O7S
Molecular Weight	517.56 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid; Piperacillin Metabolite; Piperacillinic Acid; Desethylpiperacillin; SQ 26,992; Piperacillin Impurity F (EP); Piperacillin Related Compound F (USP)
EINECS	Contact for details

Quality Control

Our Piperacilloic Acid is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for use as a reference standard and pharmaceutical intermediate. Comprehensive analysis includes identification, assay, and impurity profiling by HPLC and other orthogonal methods. Certificates of Analysis (COA) with detailed chromatographic data are provided, supporting compliance with USP/EP monographs for related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.