Description

Mesulergine is a synthetic ergoline derivative and a potent serotonin receptor antagonist with high affinity for the 5-HT2C subtype. This compound is a critical research chemical used extensively in pharmacological studies to investigate serotoninergic pathways and receptor functions. It is essential for neuroscientists, pharmacologists, and pharmaceutical R&D teams focused on central nervous system (CNS) drug discovery and neurochemical mechanism elucidation.

Application

• Neuroscience Research: A key tool compound for studying the role of 5-HT2C receptors in behavior, mood regulation, and appetite control.
• Pharmacological Profiling: Used in in vitro and in vivo assays to characterize receptor binding affinity and functional activity of new chemical entities.
• Drug Discovery & Development: Serves as a reference standard and lead compound in the development of novel therapeutics targeting serotonin receptors for CNS disorders.
• Academic Research: Employed in university and institutional labs for fundamental research into serotonin's physiological and pathological roles.
• Biochemical Reagent: Used in the preparation of receptor binding kits and other research reagents for the life science supply industry.

Basic Information

Product Name	Mesulergine
CAS No.	64795-35-3
Molecular Formula	C20H27N3O2
Molecular Weight	341.45 g/mol
Synonyms	Mesulergine; CU 32-085; 1-[(8β)-6-Methylergolin-8-yl]-3,3-diethylurea; 1-[(8β)-6-Methylergolin-8-yl]-3,3-diethylurea; Methergoline analog; 5-HT2C receptor antagonist; Serotonin antagonist CU 32-085
EINECS	Contact for details

Quality Control

Our Mesulergine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Our quality commitment supports reproducible and reliable scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.