Description

2-Hydroxyapomorphine is a significant derivative of the aporphine alkaloid class, known for its specific pharmacological profile. This compound is of high interest in advanced pharmaceutical research and development, particularly in the study of neurological pathways and receptor interactions. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring high-purity, well-characterized bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex therapeutic agents targeting the central nervous system.
• Neurological Research: Used as a reference standard and active compound in preclinical studies investigating dopamine receptor activity and related neurological mechanisms.
• Biochemical Tool Compound: Employed in in vitro assays and receptor binding studies to elucidate specific biological pathways and drug-receptor interactions.
• Reference Standard: Essential for quality control laboratories in pharmaceutical manufacturing, used for method development, calibration, and purity assessment via analytical techniques like HPLC and LC-MS.
• Academic Research: Utilized in university and institutional labs for chemical, pharmacological, and medicinal chemistry research projects.

Basic Information

Product Name	2-Hydroxyapomorphine
CAS No.	64781-18-6
Molecular Formula	C17H17NO3
Molecular Weight	283.32 g/mol
Synonyms	2-Hydroxyapomorphine; Apomorphine, 2-hydroxy-; 10,11-Dihydroxyaporphine; 2-OH-Apomorphine; (R)-2-Hydroxyapomorphine; 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-2,10,11-triol
EINECS	Contact for details

Quality Control

Our 2-Hydroxyapomorphine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and impurity profiling to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.