Description

n-(3-Chloro-4-Methylphenyl)-2,2,2-Trifluoroacetamide is a specialized trifluoroacetamide derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl groups, makes it a valuable intermediate for creating compounds with tailored electronic and steric properties. This chemical is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylated aromatic moiety.
• Agrochemical Research: Serves as a key building block for developing new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science: Used in the research and development of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for introducing the N-(3-chloro-4-methylphenyl) group into more complex molecular architectures in academic and industrial laboratories.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	n-(3-Chloro-4-Methylphenyl)-2,2,2-Trifluoroacetamide
CAS No.	64694-83-3
Molecular Formula	C9H7ClF3NO
Molecular Weight	237.61 g/mol
Synonyms	2,2,2-Trifluoro-N-(3-chloro-4-methylphenyl)acetamide; N-(3-Chloro-p-tolyl)-2,2,2-trifluoroacetamide; 3-Chloro-4-methyltrifluoroacetanilide; 2,2,2-Trifluoroacet-3'-chloro-4'-methylanilide; TFA-3-chloro-4-methylanilide; Acetamide, N-(3-chloro-4-methylphenyl)-2,2,2-trifluoro-; 64694-83-3
EINECS	Contact for details

Quality Control

Our n-(3-Chloro-4-Methylphenyl)-2,2,2-Trifluoroacetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.