Description

(2'E,7R,7'S,8S)-2',3'-Didehydro-7'-Deoxo-2'-Deoxy-7,8-Epoxy-7'-[(R)-1-Hydroxyethyl]Verrucarin A is a structurally complex macrocyclic trichothecene derivative, a class of compounds known for their potent biological activity. This high-purity reference standard is critical for advanced pharmaceutical research and analytical method development. It is primarily utilized by researchers and quality control laboratories in the life sciences sector for activities such as mycotoxin analysis, metabolic studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a certified analytical standard for the identification and quantification of verrucarin-type compounds in drug discovery and development pipelines.
• Mycotoxin Research: Used as a key reagent in studies investigating the biosynthesis, toxicity, and environmental impact of trichothecene mycotoxins.
• Metabolite Profiling: Employed in the analysis of metabolic pathways and the identification of related metabolites in biological samples.
• Bioactivity Screening: Acts as a lead compound or a control in assays designed to evaluate cytotoxic, antifungal, or other pharmacological properties.
• Analytical Method Development: Essential for validating and calibrating advanced analytical techniques such as HPLC-MS/MS and LC-UV in contract research organizations (CROs) and regulatory testing labs.

Basic Information

Product Name	(2'E,7R,7'S,8S)-2',3'-Didehydro-7'-Deoxo-2'-Deoxy-7,8-Epoxy-7'-[(R)-1-Hydroxyethyl]Verrucarin A
CAS No.	64687-83-8
Molecular Formula	C29H34O9
Molecular Weight	526.58 g/mol
Synonyms	7'-Deoxo-2'-deoxy-7,8-epoxy-7'-(1-hydroxyethyl)verrucarin A; 2',3'-Didehydro-7'-deoxo-2'-deoxy-7,8-epoxy-7'-[(R)-1-hydroxyethyl]verrucarin A; Verrucarin A derivative; Trichothecene derivative 64687-83-8; (2'E,7R,7'S,8S)-7,8-Epoxy-7'-[(R)-1-hydroxyethyl]verrucarin A derivative; Macrocyclic trichothecene; NSC 647087
EINECS	Contact for details

Quality Control

Every batch of (2'E,7R,7'S,8S)-2',3'-Didehydro-7'-Deoxo-2'-Deoxy-7,8-Epoxy-7'-[(R)-1-Hydroxyethyl]Verrucarin A is produced and handled under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC for purity and structural confirmation via spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chromatographic data is provided with each shipment to guarantee traceability and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature in a dry environment before opening to prevent condensation. The container should be kept in a cool, dry, and well-ventilated area designated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.