Description

Cefuroxime 1-Acetoxyethyl Ester CAS NO 64544-07-6 is a key pharmaceutical intermediate, specifically a prodrug ester of the second-generation cephalosporin antibiotic, Cefuroxime. This compound is critical for enhancing the bioavailability and stability of the final active pharmaceutical ingredient (API). It is primarily required by manufacturers in the pharmaceutical synthesis sector for the production of oral dosage forms of cefuroxime-based antibiotics.

Application

• Pharmaceutical Intermediate: Primary use as a prodrug in the synthesis of Cefuroxime Axetil, the oral form of the antibiotic.
• Antibiotic Manufacturing: Essential building block in the production chain for broad-spectrum cephalosporin antibiotics.
• API Synthesis: Used in controlled chemical processes to improve the drug's absorption and metabolic stability.
• Research & Development: Serves as a reference standard and starting material in pharmaceutical R&D for novel antibiotic formulations.
• Generic Drug Production: A vital component for manufacturers producing generic versions of cefuroxime medications.

Basic Information

Product Name	Cefuroxime 1-Acetoxyethyl Ester
CAS No.	64544-07-6
Molecular Formula	C20H22N4O10S
Molecular Weight	510.48 g/mol
Synonyms	(1RS)-1-Acetoxyethyl (6R,7R)-3-[(carbamoyloxy)methyl]-7-[[(Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefuroxime Axetil Intermediate; Cefuroxime 1-(Acetyloxy)ethyl Ester; Cefuroxime Acetoxyethyl Ester; Cefuroxime 1-Acetoxyethyl Ester (Cefuroxime Axetil); 1-Acetoxyethyl Cefuroxime; Cefuroxime Axetil Ester
EINECS	Contact for details

Quality Control

Our Cefuroxime 1-Acetoxyethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) are available upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.