Description

2,6-Di(tert-Butyl-D9)-4-Methylphenol-3,5,o-D3 is a deuterated isotopologue of the widely used antioxidant Butylated Hydroxytoluene (BHT). This compound is specifically designed for applications requiring stable isotope labeling, offering a non-radioactive tracer with distinct spectroscopic properties. It is primarily utilized in advanced research and analytical chemistry, particularly in pharmaceutical development and metabolic studies, where tracking molecular pathways is essential.

Application

• Internal Standard in Mass Spectrometry: Serves as a critical quantitative reference in GC-MS and LC-MS analyses for accurate measurement of BHT and related phenolic compounds.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of antioxidant stabilizers.
• Mechanistic Research: Enables detailed study of oxidation mechanisms and radical scavenging processes in polymer and fuel systems using spectroscopic techniques like NMR.
• Pharmaceutical Impurity Profiling: Assists in the identification and quantification of deuterated impurities or degradants in active pharmaceutical ingredients (APIs).
• Polymer Science Research: Acts as a labeled stabilizer to study its efficiency and migration within polymer matrices under various conditions.

Basic Information

Product Name	2,6-Di(tert-Butyl-D9)-4-Methylphenol-3,5,o-D3
CAS No.	64502-99-4
Molecular Formula	C15D21HO
Molecular Weight	225.39 g/mol (deuterated form)
Synonyms	BHT-d21; Deuterated BHT; 2,6-Bis(tert-butyl-d9)-4-methylphenol-3,5,o-d3; 3,5-Di-tert-butyl-4-hydroxytoluene-d21; Butylated Hydroxytoluene-d21; DBHT-d21; Antioxidant 264-d21; Ionol-d21
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and handled under strict quality protocols to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR and Mass Spectrometry to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical spectra is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen to maintain stability and isotopic purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Isotopic Purity (Deuterium Incorporation)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 97%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.