Description

[6R-[6Alpha,7Beta(Z)]]-3-(Acetoxymethyl)-7-[[2-(Chloroacetamido)Thiazol-4-Yl](Methoxyimino)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate, specifically a cephalosporin nucleus derivative. This compound is of critical importance for the synthesis of third-generation cephalosporin antibiotics, offering a high-purity building block for complex pharmaceutical manufacturing. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical synthesis facilities focused on advanced antibiotic production.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Core intermediate for the production of third-generation cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in the discovery and process development of new antibacterial agents.
• Fine Chemical Manufacturing: Serves as a high-value building block in multi-step organic synthesis for specialized chemical products.
• Reference Standard: Employed as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for cephalosporin-based drugs.

Basic Information

Product Name	[6R-[6Alpha,7Beta(Z)]]-3-(Acetoxymethyl)-7-[[2-(Chloroacetamido)Thiazol-4-Yl](Methoxyimino)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	64486-19-7
Molecular Formula	C20H20ClN5O8S2
Molecular Weight	557.98 g/mol
Synonyms	7-ACA Chloroacetamido Derivative; 7-ACA Chloroacetamido Methoxyimino Intermediate; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Chloroacetamide; Cephalosporin C-7 Side Chain Intermediate; GCLE Derivative; 7-ACA Chloroacetamido Methoxyimino Acetate; 7-ACCA
EINECS	Contact for details

Quality Control

Our [6R-[6Alpha,7Beta(Z)]]-3-(Acetoxymethyl)-7-[[2-(Chloroacetamido)Thiazol-4-Yl](Methoxyimino)Acetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere or in a desiccator to maintain stability. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.