Description

5-Acetyloxindole is a versatile and high-purity organic building block, specifically a functionalized oxindole derivative, essential for advanced synthetic chemistry. Its core value lies in serving as a critical precursor for the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other bioactive molecules targeting central nervous system and oncological pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides and plant growth regulators that leverage the oxindole scaffold.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, cyclizations, and as a starting material for more complex fused heterocycles like spirooxindoles.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors and functional dyes due to its electron-rich aromatic system.
• Academic & R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	5-Acetyloxindole
CAS No.	64483-69-8
Molecular Formula	C10H9NO2
Molecular Weight	175.18 g/mol
Synonyms	1-(2,3-Dihydro-5-hydroxy-2-oxo-1H-indol-3-yl)ethanone; 5-Acetyl-1,3-dihydro-2H-indol-2-one; 5-Acetylindolin-2-one; 3-Acetyl-5-hydroxyoxindole; 5-Acetyloxindole; 5-Acetyl-2-indolinone
EINECS	Contact for details

Quality Control

Our 5-Acetyloxindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.