Description

2-((4-(tert-Butyl)Phenyl)Sulfonyl)Acetonitrile is a specialized organic intermediate featuring a sulfonyl acetonitrile functional group attached to a tert-butyl substituted aromatic ring. This molecular structure makes it a valuable building block for the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound's reactivity profile allows for further functionalization, enabling the creation of targeted chemical libraries for screening and development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring sulfonamide or heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its aromatic and sulfonyl components.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with specific electronic or structural properties.
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis or metal-organic frameworks (MOFs) due to its potential coordination sites.
• Chemical Biology Probes: Utilized as a starting material for creating fluorescent tags or activity-based probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-((4-(tert-Butyl)Phenyl)Sulfonyl)Acetonitrile
CAS No.	64445-04-1
Molecular Formula	C₁₂H₁₅NO₂S
Molecular Weight	237.32 g/mol
Synonyms	2-[(4-tert-Butylphenyl)sulfonyl]acetonitrile; 2-((p-tert-Butylphenyl)sulfonyl)acetonitrile; Acetonitrile, 2-[(4-(1,1-dimethylethyl)phenyl]sulfonyl]-; 2-(4-tert-Butylbenzenesulfonyl)acetonitrile; p-tert-Butylphenylsulfonylacetonitrile; 4-tert-Butylbenzenesulfonylacetonitrile; (4-(tert-Butyl)phenylsulfonyl)acetonitrile
EINECS	Contact for details

Quality Control

Our production of 2-((4-(tert-Butyl)Phenyl)Sulfonyl)Acetonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and tested against rigorous in-house specifications, which typically include identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We are committed to supporting our clients' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.