Description

Acetylated Concanavalin A is a chemically modified derivative of the plant lectin Concanavalin A, where specific amino acid residues have been acetylated to alter its binding properties and stability. This modification is critical for enhancing its utility in advanced biochemical and biomedical research applications where precise carbohydrate recognition is required. It is an essential reagent for researchers and manufacturers in the fields of glycobiology, immunology, and diagnostic assay development, particularly for lectin-based affinity chromatography and cell separation techniques.

Application

• Affinity Chromatography: Used as a ligand for the purification of glycoproteins, polysaccharides, and glycolipids based on specific carbohydrate interactions.
• Cell Separation and Analysis: Employed in flow cytometry and magnetic-activated cell sorting (MACS) to isolate specific cell populations based on surface glycan markers.
• Diagnostic Assays: Serves as a key component in lectin-based biosensors and ELISA for detecting disease-specific glycan biomarkers.
• Glycobiology Research: A fundamental tool for studying carbohydrate-protein interactions, cell surface architecture, and glycosylation patterns.
• Immunology Studies: Used to investigate lymphocyte activation and membrane receptor dynamics due to its mitogenic properties.
• Biomaterial and Drug Delivery: Incorporated into functionalized surfaces or nanoparticles for targeted delivery systems.

Basic Information

Product Name	Acetylated Concanavalin A
CAS No.	64425-91-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Acetyl-Con A; Ac-Con A; N-Acetylated Concanavalin A; Concanavalin A, acetylated; Jack bean lectin, acetylated derivative; α-D-mannosyl-/α-D-glucosyl-binding lectin, acetylated; Affinity purified acetylated Concanavalin A
EINECS	Contact for details

Quality Control

Our Acetylated Concanavalin A is produced under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including assessment of purity, protein content, and specific carbohydrate-binding activity. Certificates of Analysis (COA) documenting these specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to standard
Protein Content (Biuret)	≥ 90%
Purity (SDS-PAGE)	≥ 95%
Hemagglutination Activity	Defined units/mg protein
Carbohydrate Binding Specificity	Confirmed
Endotoxin Level (LAL)	< 10 EU/mg
Solubility	Soluble in water and buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.