Description

3-(Trifluoromethyl)Cinnamide is a high-value fluorinated organic intermediate characterized by its cinnamide backbone and trifluoromethyl substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical building block in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals where fluorine incorporation modifies physical properties.
• Organic Synthesis: A versatile reagent for constructing complex molecules via amide coupling and cross-coupling reactions.
• Biochemical Tool Compound: Used in academic and industrial research to study enzyme interactions and biological pathways.

Basic Information

Product Name	3-(Trifluoromethyl)Cinnamide
CAS No.	64380-24-1
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	3-(Trifluoromethyl)cinnamic acid amide; (E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enamide; α-(Trifluoromethyl)cinnamamide; 3-(Trifluoromethyl)benzeneacrylamide; 3-(Trifluoromethyl)cinnamein; 3-Trifluoromethylcinnamamide; (E)-3-(3-(Trifluoromethyl)phenyl)acrylamide
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Cinnamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.