Description

3-(3-Fluorophenyl)-2-Propenamide is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the fluorine atom is strategically incorporated to modulate biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorophenyl moiety can enhance efficacy and environmental profile.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers and advanced materials with tailored optical or electronic properties.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a scaffold for constructing more complex heterocyclic compounds in medicinal chemistry.
• Bioconjugation & Probe Development: Utilized in the design of fluorescent probes, affinity labels, and other biochemical tools for life science research.

Basic Information

Product Name	3-(3-Fluorophenyl)-2-Propenamide
CAS No.	64379-96-0
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	(E)-3-(3-Fluorophenyl)acrylamide; 3-Fluorocinnamamide; trans-3-(3-Fluorophenyl)acrylamide; (E)-3-(3-Fluorophenyl)prop-2-enamide; 3-(3-Fluorophenyl)-2-propenoic acid amide; 3-Fluorocinnameic acid amide; NSC 403714; AI3-52511
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-2-Propenamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.