Description

4-(Hydroxymethyl)Pyrrolidin-2-One is a versatile heterocyclic building block featuring both a lactam ring and a hydroxymethyl functional group. This bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists working on novel active ingredients. The compound, identified by CAS No. 64320-89-4, is essential for constructing pyrrolidine-based scaffolds with enhanced solubility and biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core.
• Chiral Auxiliary & Ligand Precursor: Serves as a starting material for synthesizing chiral catalysts and ligands used in asymmetric synthesis.
• Polymer Modification: Acts as a monomer or cross-linking agent for specialty polymers, imparting specific functional properties.
• Bioconjugation Chemistry: The hydroxymethyl group facilitates linking to other molecules, useful in probe and diagnostic reagent development.
• Chemical Research & Development: A fundamental building block in medicinal chemistry and organic synthesis for exploring new chemical spaces.

Basic Information

Product Name	4-(Hydroxymethyl)Pyrrolidin-2-One
CAS No.	64320-89-4
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	2-Pyrrolidinone, 4-(hydroxymethyl)-; 4-(Hydroxymethyl)-2-pyrrolidinone; 4-Hydroxymethyl-2-pyrrolidone; (4-Hydroxymethyl)pyrrolidin-2-one; 4-Hydroxymethylpyrrolidin-2-one; 2-Oxo-4-pyrrolidinemethanol; 4-Pyrrolidinemethanol, 2-oxo-
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.