Description

Boc-N-Me-Ser(Bzl)-OH is a protected, non-proteinogenic amino acid derivative essential for advanced peptide synthesis. This compound is specifically engineered to introduce N-methyl-serine residues into peptide chains, a modification critical for enhancing metabolic stability, bioavailability, and biological activity. It is a vital building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic peptides, peptidomimetics, and drug candidates.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of N-methyl-serine into peptide sequences.
• Pharmaceutical Research: Used in the development of peptide-based drugs where N-methylation improves resistance to enzymatic degradation.
• Peptidomimetic Design: Serves as a crucial scaffold for creating molecules that mimic natural peptides with enhanced drug-like properties.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Bioconjugation: Can be used as a linker or modified component in the synthesis of peptide-drug conjugates or labeled peptides.
• Academic & Industrial R&D: Fundamental reagent for studying structure-activity relationships (SAR) in peptide science.

Basic Information

Product Name	Boc-N-Me-Ser(Bzl)-OH
CAS No.	64263-84-9
Molecular Formula	C16H23NO5
Molecular Weight	309.36 g/mol
Synonyms	N-[(tert-Butoxy)carbonyl]-N-methyl-O-benzyl-L-serine; Boc-N-methyl-O-benzyl-L-serine; (2S)-3-(Benzyloxy)-2-[(tert-butoxycarbonyl)(methyl)amino]propanoic acid; Boc-N-Me-Ser(Bzl)-OH; Boc-N-Methyl-O-benzyl-L-serine; tert-Butyl N-methyl-N-[(2S)-3-(benzyloxy)-1-hydroxy-1-oxopropan-2-yl]carbamate; N-Boc-N-methyl-O-benzylserine
EINECS	Contact for details

Quality Control

Our Boc-N-Me-Ser(Bzl)-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity ([α]D)	≥99.0% ee
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.