Description

(7S)-7-[(4-Carboxy-1-Oxobutyl)Amino]-7-Methoxy-3-[[(1,3,4-Thiadiazol-2-Yl)Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid is a key advanced pharmaceutical intermediate, specifically a cephem derivative, used in the synthesis of modern cephalosporin antibiotics. Its complex structure provides the essential scaffold for developing potent antibacterial agents with enhanced stability and efficacy. This high-purity intermediate is critical for manufacturers in the pharmaceutical industry focused on producing next-generation β-lactam antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the multi-step synthesis of advanced cephalosporin antibiotics.
• Antibacterial Drug Development: Serves as a core structural component for research and development of new antibacterial agents targeting resistant pathogens.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the final stages or penultimate steps of API manufacturing for specific cephalosporin drugs.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale production for new antibiotic formulations.
• Biochemical Research: Utilized in academic and industrial research to study structure-activity relationships (SAR) within the β-lactam class of antibiotics.

Basic Information

Item	Details
Product Name	(7S)-7-[(4-Carboxy-1-Oxobutyl)Amino]-7-Methoxy-3-[[(1,3,4-Thiadiazol-2-Yl)Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid
CAS No.	64219-29-0
Molecular Formula	C17H20N4O7S2
Molecular Weight	456.49 g/mol
Synonyms	7-Methoxy-7-[(4-carboxy-1-oxobutyl)amino]-3-[(1,3,4-thiadiazol-2-ylthio)methyl]cephem-4-carboxylic acid; Cephem intermediate 64219-29-0; 3-[(1,3,4-Thiadiazol-2-ylthio)methyl]-7-methoxy-7-[(4-carboxybutanoyl)amino]-3-cephem-4-carboxylic acid; 7β-[(4-Carboxybutanamido)]-7α-methoxy-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic acid; (6R,7S)-7-[(4-Carboxybutanamido)]-7-methoxy-3-[(1,3,4-thiadiazol-2-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our (7S)-7-[(4-Carboxy-1-Oxobutyl)Amino]-7-Methoxy-3-[[(1,3,4-Thiadiazol-2-Yl)Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high-purity standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting compliance with cGMP and internal quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.