Description

(7S)-7-[(4-Carboxy-1-Oxobutyl)Amino]-7-Methoxy-3-[[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid is a key advanced pharmaceutical intermediate in the cephalosporin antibiotic class. Its value lies in its role as a crucial building block for synthesizing potent, broad-spectrum antibiotics, directly impacting drug efficacy and manufacturing scalability. This compound is essential for pharmaceutical R&D laboratories and manufacturers focused on developing and producing next-generation antibacterial agents to meet global healthcare demands.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary use as a critical intermediate in the production of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Serves as a key scaffold for medicinal chemists exploring new antibacterial compounds with improved spectra and resistance profiles.
• Process Chemistry & Scale-Up: Utilized in optimizing synthetic routes for the cost-effective and reliable manufacturing of final drug substances.
• Antibacterial Agent Formulation: Integral to the development of injectable and other dosage forms targeting serious bacterial infections.

Basic Information

Product Name	(7S)-7-[(4-Carboxy-1-Oxobutyl)Amino]-7-Methoxy-3-[[(5-Methyl-1,3,4-Thiadiazol-2-Yl)Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid
CAS No.	64219-28-9
Molecular Formula	C₁₉H₂₄N₄O₇S₃
Molecular Weight	516.60 g/mol
Synonyms	7-Methoxy-7-[(4-carboxy-1-oxobutyl)amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-3-cephem-4-carboxylic Acid; Cefmenoxime Intermediate; Cefmenoxime Impurity; (6R,7S)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Related Compound; SCE-1365 Intermediate; 7β-[(Z)-2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-3-cephem-4-carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of this high-value pharmaceutical intermediate adheres to strict cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through comprehensive analytical methods including HPLC for purity and assay, identification by spectroscopic techniques, and rigorous control of specified impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.