Description

(7S)-7-[(4-Carboxy-1-Oxobutyl)Amino]-7-Methoxy-3-[[[5-[(Carboxymethyl)Thio]-1,3,4-Thiadiazol-2-Yl]Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the cephem class of β-lactam antibiotics. This compound is critical for the research and development of next-generation antibacterial agents, offering a sophisticated chemical scaffold for further synthetic modification. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antimicrobial drug discovery.

Application

• Key Intermediate in Antibiotic Synthesis: Serves as a crucial building block in the multi-step synthesis of novel cephalosporin and cephamycin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry programs to develop new antibacterial compounds with improved efficacy and spectrum of activity.
• Structure-Activity Relationship (SAR) Studies: The complex molecular structure allows researchers to investigate the impact of specific functional groups on biological activity.
• Fine Chemical Manufacturing: Employed in the production of high-value, specialized active pharmaceutical ingredients (APIs) for clinical trials.
• Biochemical Research: Used as a tool compound in studies targeting bacterial cell wall synthesis and β-lactam resistance mechanisms.

Basic Information

Item	Details
Product Name	(7S)-7-[(4-Carboxy-1-Oxobutyl)Amino]-7-Methoxy-3-[[[5-[(Carboxymethyl)Thio]-1,3,4-Thiadiazol-2-Yl]Thio]Methyl]Cepham-3-Ene-4-Carboxylic Acid
CAS No.	64219-26-7
Molecular Formula	C₂₁H₂₄N₆O₉S₃
Molecular Weight	608.64 g/mol
Synonyms	7-Methoxy-7-[(4-carboxy-1-oxobutyl)amino]-3-[[[5-[(carboxymethyl)thio]-1,3,4-thiadiazol-2-yl]thio]methyl]-3-cephem-4-carboxylic acid; Cephem derivative 64219-26-7; 3-[[[5-[(Carboxymethyl)thio]-1,3,4-thiadiazol-2-yl]thio]methyl]-7-methoxy-7-[(4-carboxy-1-oxobutyl)amino]-3-cephem-4-carboxylic acid; (6R,7S)-7-[(4-Carboxy-1-oxobutyl)amino]-7-methoxy-3-[[[5-[(carboxymethyl)thio]-1,3,4-thiadiazol-2-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Advanced cephem intermediate; Antibiotic research intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.