Description

Uracil Permease, S Cerevisiae is a specialized membrane transport protein derived from the yeast *Saccharomyces cerevisiae* that facilitates the uptake of uracil and related pyrimidine compounds. This product is critical for research and development in molecular biology, genetics, and metabolic engineering, enabling precise studies of nucleoside transport mechanisms and cellular metabolism. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies involved in yeast-based systems, pathway analysis, and the development of novel bio-production platforms.

Application

• Molecular Biology Research: Essential for studying pyrimidine uptake, gene regulation, and membrane protein function in *S. cerevisiae*.
• Metabolic Engineering: Used in the design and optimization of yeast strains for the production of nucleotides, nucleosides, and related fine chemicals.
• Functional Genomics: Serves as a key tool in functional assays to characterize transporter activity and screen for genetic modifiers.
• Drug Discovery Platforms: Incorporated into yeast-based assays to identify and evaluate potential inhibitors of nucleoside transport for therapeutic development.
• Biochemical Reagent: Employed as a purified protein component in in vitro reconstitution studies of transport kinetics and mechanism.
• Educational & Diagnostic Kits: Supplied as a reference standard in advanced educational kits and diagnostic assays for microbiology and biochemistry.

Basic Information

Item	Details
Product Name	Uracil Permease, S Cerevisiae
CAS No.	64177-90-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FUR4 Permease; Uracil transporter FUR4; S. cerevisiae uracil permease; FUR4 protein; Pyrimidine permease; Uracil-specific permease; Nucleoside uptake protein FUR4; Yeast uracil transporter
EINECS	Contact for details

Quality Control

Our Uracil Permease, S Cerevisiae is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous analytical testing, including assessment of purity, protein concentration, and functional activity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific activity is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture. Avoid repeated freeze-thaw cycles to maintain protein integrity.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (SDS-PAGE)	Single major band at appropriate molecular weight
Purity (HPLC)	≥ 90%
Protein Concentration	As per COA
Specific Activity	As per COA
Endotoxin Level	< 1.0 EU/µg (if applicable)
Solubility	Reconstitutes in suitable buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.