Description

n-o-Nps-L-Glutamine, Dicyclohexylammonium Salt is a protected derivative of the amino acid L-glutamine, where the amine functionality is shielded by the o-nitrophenylsulfenyl (Nps) group. This chemical modification is crucial for enabling selective peptide bond formation in complex solid-phase peptide synthesis (SPPS), preventing unwanted side reactions. It is an essential building block for research chemists and manufacturers developing therapeutic peptides, bioactive compounds, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key protected glutamine residue for the controlled, sequential assembly of peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, hormones, and diagnostic agents.
• Bioconjugation: Acts as a specialized intermediate for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening and drug discovery.
• Academic & Industrial Research: A fundamental reagent for studying peptide structure, function, and synthesis methodologies.

Basic Information

Item	Details
Product Name	n-o-Nps-L-Glutamine, Dicyclohexylammonium Salt
CAS No.	64143-47-1
Molecular Formula	C23H37N3O5S
Molecular Weight	467.62 g/mol
Synonyms	N-2-Nitrophenylsulfenyl-L-glutamine Dicyclohexylammonium Salt; (S)-2-((2-Nitrophenylthio)carbamoyl)pentanediamic Acid Dicyclohexylammonium Salt; Nps-Gln-OH·DCHA; o-NPS-L-Glutamine Dicyclohexylamine Salt; L-Glutamine, N-[(2-nitrophenyl)thio]-, compd. with N-cyclohexylcyclohexanamine (1:1); N-2-Nitrophenylsulfenylglutamine DCHA Salt; Protected L-Glutamine DCHA Salt
EINECS	Contact for details

Quality Control

Every batch of n-o-Nps-L-Glutamine, Dicyclohexylammonium Salt is manufactured and tested under strict quality management systems. We ensure high purity and consistency through comprehensive analytical protocols, including HPLC, NMR, and chiral analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Specific range available on COA
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.