Description

[As,(-)]-2,2'-Bis[(Diphenylphosphino)Methyl]-1,1'-Binaphthalene is a chiral, atropisomeric diphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, providing a critical tool for the synthesis of single-enantiomer compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
• As a key component in catalysts for asymmetric C-C bond-forming reactions, such as cross-coupling and allylic alkylation.
• In the synthesis of enantiomerically pure pharmaceutical intermediates and active ingredients.
• For the development of novel catalytic systems in academic and industrial R&D settings.
• In the production of specialty agrochemicals and flavors & fragrances requiring chiral purity.
• As a reference standard for method development in analytical chemistry for chiral separation.

Basic Information

Product Name	[As,(-)]-2,2'-Bis[(Diphenylphosphino)Methyl]-1,1'-Binaphthalene
CAS No.	64091-23-2
Molecular Formula	C46H36P2
Molecular Weight	650.73 g/mol
Synonyms	(-)-2,2'-Bis[(Diphenylphosphino)Methyl]-1,1'-Binaphthyl; (aS)-BINAP-Me; (aS)-2,2'-Bis(diphenylphosphinomethyl)-1,1'-binaphthyl; (aS)-MeO-BIPHEP (common misnomer); (aS)-2,2'-Bis(diphenylphosphanylmethyl)-1,1'-binaphthalene; (aS)-DIPHOS-BINAPH; As-BINAP-Me; (aS)-BINAP-M
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity chiral ligands. Each batch is characterized to confirm identity, enantiomeric purity, and chemical purity. Certificates of Analysis (COA) detailing specific analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.