Description

N,n-Bis[2-[(S)-2,2,4-Trimethyl-1,3-Dioxolan-4-Yl]Ethyl]Acetamide is a specialized chiral intermediate featuring a protected diol functionality, which is critical for synthesizing complex molecules with high stereochemical purity. This compound matters because it provides a versatile building block for the controlled introduction of specific stereocenters and functional groups in advanced chemical synthesis. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and high-value specialty chemicals where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where biological activity is stereospecific.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and Industrial Research: A valuable tool for chemists in R&D laboratories exploring new synthetic methodologies and novel molecular entities.
• Material Science Precursor: Potential use in creating chiral polymers or advanced organic materials with specific optical properties.

Basic Information

Product Name	N,n-Bis[2-[(S)-2,2,4-Trimethyl-1,3-Dioxolan-4-Yl]Ethyl]Acetamide
CAS No.	64061-18-3
Molecular Formula	C19H35NO5
Molecular Weight	357.49 g/mol
Synonyms	Acetamide, N,N-bis[2-[(4S)-2,2,4-trimethyl-1,3-dioxolan-4-yl]ethyl]-; (S)-N,N-Bis[2-(2,2,4-trimethyl-1,3-dioxolan-4-yl)ethyl]acetamide; 1,3-Dioxolane-4-ethanol, 2,2,4-trimethyl-, 4,4'-[iminobis(ethyleneoxy-2,1-ethanediyl)]bis[(4S)-; Chiral Dioxolane Acetamide Derivative; (S)-Protected Diol Bis-Acetamide; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our N,n-Bis[2-[(S)-2,2,4-Trimethyl-1,3-Dioxolan-4-Yl]Ethyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for advanced synthetic intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.