Description

Osteoclast Activating Factor is a biologically active peptide involved in the regulation of bone metabolism. This compound is of significant interest in biomedical research for its role in stimulating osteoclast-mediated bone resorption. It is primarily utilized by researchers and pharmaceutical developers in the fields of osteoporosis, bone cancer, and metabolic bone disease studies to investigate pathological mechanisms and potential therapeutic targets.

Application

• Biomedical Research: Fundamental studies on bone remodeling, osteoclast differentiation, and activation pathways.
• Drug Discovery: Screening and validation of novel therapeutic agents targeting excessive bone resorption in conditions like osteoporosis.
• Disease Modeling: Used in in vitro and in vivo models to study bone metastasis associated with cancers.
• Academic Research: Tool compound for university and institutional labs focusing on skeletal biology and endocrinology.
• Biomarker Studies: Investigation of its role as a potential biomarker for bone turnover rates.
• Assay Development: Critical component in developing bioassays to measure osteoclast activity and inhibitor efficacy.

Basic Information

Product Name	Osteoclast Activating Factor
CAS No.	64060-24-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	OAF; Osteoclast Activating Factor (OAF); Parathyroid Hormone-Related Protein Fragment; PTHrP Fragment; Bone Resorption Factor; Lymphokine OAF; Osteolytic Factor
EINECS	Contact for details

Quality Control

Our Osteoclast Activating Factor is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and biological activity. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and bioactivity are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake. Aliquot into smaller working quantities to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Determined by osteoclast resorption assay
Endotoxin Level	< 1.0 EU/µg
Water Content (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.