Description

N,N'-(2-Hydroxytrimethylene)Bis(Iodoacetamide) is a specialized bifunctional alkylating agent featuring iodoacetamide groups linked by a hydroxytrimethylene spacer. This compound is valued for its ability to introduce specific cross-links or modifications into biomolecules, making it a critical reagent in advanced research and development. It is primarily utilized by scientists and process developers in the pharmaceutical, biotechnology, and life science sectors for applications such as protein structure analysis, enzyme inhibition studies, and the synthesis of novel chemical probes.

Application

• Protein Cross-linking and Modification: Used as a heterobifunctional cross-linker to study protein-protein interactions or to introduce stable modifications for structural analysis.
• Enzyme Active Site Probing: Acts as an affinity label to covalently modify cysteine or other nucleophilic residues in enzyme active sites for mechanistic studies.
• Bioconjugation Reagent: Facilitates the site-specific attachment of labels, drugs, or other molecules to proteins, antibodies, or peptides.
• Polymer and Material Science: Serves as a monomer or cross-linking agent in the synthesis of functionalized polymers and hydrogels with tailored properties.
• Pharmaceutical Intermediate: Employed in the research and development of novel therapeutic agents, particularly in targeted drug delivery systems.
• Chemical Biology Tool: Used to create chemical probes for investigating biological pathways and cellular processes.

Basic Information

Product Name	N,N'-(2-Hydroxytrimethylene)Bis(Iodoacetamide)
CAS No.	64049-32-7
Molecular Formula	C7H11I2N2O3
Molecular Weight	439.98 g/mol
Synonyms	1,3-Bis(iodoacetamido)-2-propanol; 2-Hydroxy-1,3-propanediylbis(iodoacetamide); N,N'-(2-Hydroxy-1,3-propanediyl)bis(2-iodoacetamide); Bis(iodoacetamido)propanol; Iodoacetamide Hydroxytrimethylene Dimer
EINECS	Contact for details

Quality Control

Our N,N'-(2-Hydroxytrimethylene)Bis(Iodoacetamide) is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our customers in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.