Description

N,N'-Di-tert-Butylcyclobutane-1,2-Dicarboxamide is a specialized organic compound featuring a cyclobutane core symmetrically substituted with tert-butylamide groups. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex, sterically hindered molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications requiring high-purity, custom-tailored intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring rigid, sterically defined architectures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where its structural motif can impart specific biological activity.
• Ligand and Catalyst Development: Acts as a precursor or core structure for designing novel ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of specialty polymers or organic frameworks where the cyclobutane and amide groups contribute to material properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions of strained systems.

Basic Information

Product Name	N,N'-Di-tert-Butylcyclobutane-1,2-Dicarboxamide
CAS No.	64011-95-6
Molecular Formula	C16H30N2O2
Molecular Weight	282.43 g/mol
Synonyms	1,2-Cyclobutanedicarboxamide, N,N'-bis(1,1-dimethylethyl)-; N,N'-Di-tert-butyl-1,2-cyclobutanedicarboxamide; Di-tert-butylcyclobutane-1,2-dicarboxamide; 1,2-Cyclobutanedicarboxylic acid bis(tert-butylamide); N,N'-Di-t-butylcyclobutane-1,2-dicarboxamide; Cyclobutane-1,2-dicarboxylic acid di-tert-butylamide; (1R,2R)-rel-N,N'-Bis(1,1-dimethylethyl)-1,2-cyclobutanedicarboxamide
EINECS	Contact for details

Quality Control

Our N,N'-Di-tert-Butylcyclobutane-1,2-Dicarboxamide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with relevant ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.