Description

Indapamide Related Compound A (50 Mg) (4-Chloro-n-(2-Methyl-Indol-1-Yl)-3-Sulfamoylben-Zamide) (As) is a high-purity analytical reference standard, essential for pharmaceutical research and quality control. This compound serves as a critical impurity marker for the validation and monitoring of the antihypertensive drug Indapamide, ensuring product safety and regulatory compliance. It is primarily required by analytical laboratories, pharmaceutical manufacturers, and regulatory bodies for method development, stability studies, and batch release testing. The material is supplied as a precisely weighed 50 mg quantity to guarantee accuracy and convenience in laboratory use.

Application

• Pharmaceutical Impurity Profiling and Identification in Indapamide API and finished dosage forms.
• Analytical Method Development and Validation (HPLC, UPLC, GC) for regulatory submissions.
• Stability-Indicating Assay to monitor degradation pathways in drug products.
• Quality Control Reference Standard for in-house testing and batch release.
• Pharmacopoeial Testing to comply with USP, EP, or other international monograph requirements.
• Research and Development of generic formulations and process chemistry.
• Calibration of Laboratory Equipment for precise quantitative analysis.

Basic Information

Product Name	Indapamide Related Compound A (50 Mg) (4-Chloro-n-(2-Methyl-Indol-1-Yl)-3-Sulfamoylben-Zamide) (As)
CAS No.	63968-75-2
Molecular Formula	C16H14ClN3O3S
Molecular Weight	363.82 g/mol
Synonyms	4-Chloro-N-(2-methyl-1H-indol-1-yl)-3-sulfamoylbenzamide; Indapamide Impurity A; Indapamide Related Substance A; 1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindole; Benzamide, 4-chloro-N-(2-methyl-1H-indol-1-yl)-3-sulfamoyl-; Indapamide EP Impurity A; Indapamide USP Related Compound A
EINECS	Contact for details

Quality Control

This high-grade reference material is produced under strict quality management systems. Each batch is characterized using advanced spectroscopic and chromatographic techniques, including NMR, MS, and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is supplied, detailing batch-specific results for assay, related substances, and residual solvents. Our quality standards are designed to meet the rigorous demands of pharmaceutical analysis and regulatory compliance (e.g., ICH guidelines).

Storage

Preserve in the original tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. Avoid frequent temperature fluctuations to maintain long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0% w/w
Residual Solvents (GC)	Complies with ICH Q3C
Net Content	50 mg ± 2 mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.