Description

Procainamide is a class Ia antiarrhythmic agent, a sodium channel blocker used to treat cardiac arrhythmias. Its primary value lies in its ability to stabilize the cardiac membrane and prolong the action potential duration, making it a critical pharmaceutical intermediate for the synthesis of life-saving medications. This compound is essential for manufacturers in the pharmaceutical and fine chemical sectors, particularly those developing and producing cardiovascular drugs.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in antiarrhythmic medications for treating ventricular and supraventricular arrhythmias.
• Research & Development: A key reference standard and building block in cardiovascular drug discovery and pharmacological studies.
• Chemical Synthesis: Serves as a crucial intermediate for the preparation of more complex antiarrhythmic agents and related pharmaceutical compounds.
• Clinical Formulations: Used in the production of various dosage forms, including injectable solutions and oral tablets.
• Metabolite Studies: Important for pharmacokinetic research and the study of its active metabolite, N-acetylprocainamide (NAPA).

Basic Information

Product Name	Procainamide
CAS No.	63887-34-3
Molecular Formula	C13H21N3O
Molecular Weight	235.33 g/mol
Synonyms	Procainamide Hydrochloride (common salt form); 4-Amino-N-[2-(diethylamino)ethyl]benzamide; Procainamide HCl; Pronestyl; Procan SR; Novocainamide; Procamide; Procapan
EINECS	Contact for details

Quality Control

Our Procainamide is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. We offer grades compliant with pharmacopoeial standards (e.g., USP, EP). Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request to ensure your regulatory compliance and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥98.0% - 102.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.