Description

1,2,3,6-Tetrahydro-4-Ethynyl-1,2,2,6,6-Pentamethylpyridine is a specialized heterocyclic organic compound featuring a unique ethynyl-substituted piperidine core. This compound serves as a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of complex molecular architectures. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Building block for developing advanced crop protection agents and pesticides with specific activity profiles.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for transition metal catalysis and asymmetric synthesis.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, dyes, and functional polymers.
• Academic and Industrial R&D: Serves as a critical starting material for research in medicinal chemistry and material science.
• Chemical Probes and Tool Compounds: Utilized in the development of biochemical probes for studying enzyme function and receptor interactions.

Basic Information

Item	Detail
Product Name	1,2,3,6-Tetrahydro-4-Ethynyl-1,2,2,6,6-Pentamethylpyridine
CAS No.	63867-74-3
Molecular Formula	C12H19N
Molecular Weight	177.29 g/mol
Synonyms	4-Ethynyl-1,2,2,6,6-pentamethyl-1,2,3,6-tetrahydropyridine; 4-Ethynyl-1,2,2,6,6-pentamethyl-3,6-dihydro-2H-pyridine; 1,2,2,6,6-Pentamethyl-4-ethynyl-3,6-dihydro-2H-pyridine; 4-Ethynyl-1,2,2,6,6-pentamethylpiperidine (tautomer reference); Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our 1,2,3,6-Tetrahydro-4-Ethynyl-1,2,2,6,6-Pentamethylpyridine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We are committed to meeting the stringent requirements for GMP-grade intermediates and can support custom purity specifications for your project.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.