Description

Cefoxitin Sodium CAS NO 63824-86-2 is a semi-synthetic, broad-spectrum cephamycin antibiotic derived from cephamycin C. It is valued for its stability against β-lactamase enzymes, making it a critical agent in combating resistant bacterial strains. This injectable antibiotic is essential for pharmaceutical manufacturers and research institutions developing sterile parenteral formulations for hospital and clinical use.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of sterile injectable antibiotic formulations.
• Hospital Infection Treatment: Used in drugs targeting mixed aerobic-anaerobic infections, including intra-abdominal and gynecological infections.
• Surgical Prophylaxis: Key component in pre- and post-operative antibiotics to prevent surgical site infections.
• Bacteriological Research: Used as a reference standard and selective agent in microbiological studies and antimicrobial susceptibility testing.
• Veterinary Medicine: Employed in certain veterinary pharmaceutical preparations for bacterial infections in animals.

Basic Information

Product Name	Cefoxitin Sodium
CAS No.	63824-86-2
Molecular Formula	C16H16N3NaO7S2
Molecular Weight	449.43 g/mol
Synonyms	Cefoxitin Sodium Salt; Sodium Cefoxitin; (6R,7S)-3-(Carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; Mefoxin; Cefoxitin Na; Cefoxitin Sodium USP; Cefoxitin Sodium EP; 3-[(Aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
EINECS	264-430-5

Quality Control

Our Cefoxitin Sodium is manufactured under strict quality systems and tested to meet or exceed relevant pharmacopeial standards, including USP and EP monographs. Each batch undergoes rigorous analytical testing for identity, potency, purity, and sterility-related parameters. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	4.2 - 7.0
Water Content (KF)	≤ 1.5%
Specific Optical Rotation	+212° to +222°
Related Substances (HPLC)	Individual Impurity: ≤ 1.0% Total Impurities: ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.