Description

3β-[(6-Deoxy-3-o-Methyl-D-Glucopyranosyl)Oxy]-14,16β-Dihydroxy-19-Oxo-5α-Bufa-20,22-Dienolide is a high-purity bufadienolide glycoside, a class of compounds known for their significant biological activity. This compound is valued for its role as a critical reference standard and advanced pharmaceutical intermediate in research and development. It is primarily needed by organizations in the pharmaceutical, biotechnology, and academic research sectors focused on cardiology, oncology, and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of bufadienolide-based drugs and natural extracts in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of specialized cardiac and anticancer therapeutics.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate Na+/K+-ATPase inhibition, cell signaling pathways, and apoptosis mechanisms.
• Natural Product Isolation & Standardization: Acts as a calibration marker for the identification and quantification of related compounds in toad venom and traditional medicine preparations.
• Preclinical Drug Development: Utilized in pharmacological screening and toxicology studies to evaluate efficacy and safety profiles of new drug candidates.

Basic Information

Product Name	3β-[(6-Deoxy-3-o-Methyl-D-Glucopyranosyl)Oxy]-14,16β-Dihydroxy-19-Oxo-5α-Bufa-20,22-Dienolide
CAS No.	63765-68-4
Molecular Formula	C31H44O10
Molecular Weight	576.68 g/mol
Synonyms	3β-[(6-Deoxy-3-O-methyl-D-glucopyranosyl)oxy]-14,16β-dihydroxy-19-oxo-5α-bufa-20,22-dienolide; Bufalin 3-O-(6-deoxy-3-O-methyl-β-D-glucopyranoside); 19-Oxobufalin 3-O-β-D-thevetoside; A Bufadienolide Glycoside; Gamabufotalin 3-O-β-D-thevetoside; 14,16β-Dihydroxy-19-oxobufa-20,22-dienolide 3-O-(6-deoxy-3-O-methyl-β-D-glucopyranoside); 3-[(6-Deoxy-3-O-methyl-β-D-glucopyranosyl)oxy]-14,16-dihydroxy-19-oxobufa-20,22-dienolide
EINECS	Contact for details

Quality Control

Our 3β-[(6-Deoxy-3-o-Methyl-D-Glucopyranosyl)Oxy]-14,16β-Dihydroxy-19-Oxo-5α-Bufa-20,22-Dienolide is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.