Description

Actovegin is a highly purified, standardized deproteinized hemodialysate derived from calf blood, widely recognized for its tissue repair and metabolic enhancement properties. Its primary value lies in its ability to improve cellular oxygen uptake and utilization, which is critical for supporting healing processes under compromised metabolic conditions. This makes it an essential component in the formulation of pharmaceutical products targeting wound healing, circulatory disorders, and specific neurological conditions. Actovegin CAS NO 63748-11-8 is a key active pharmaceutical ingredient (API) for manufacturers in the global pharmaceutical and advanced medical research sectors.

Application

• Pharmaceutical API: Core ingredient in injectable solutions, infusions, and topical formulations for the treatment of impaired wound healing (e.g., ulcers, burns).
• Metabolic Disorders: Used in medications aimed at improving glucose utilization in diabetic polyneuropathy and other peripheral circulatory disorders.
• Neurological Support: Incorporated into therapies for cognitive impairment and sequelae of stroke, leveraging its neuroprotective and metabolic effects.
• Ophthalmic Preparations: Formulated in eye drops and gels for treating corneal lesions and other degenerative conditions of the cornea.
• Dermatology & Cosmeceuticals: Used in advanced creams and gels for skin regeneration, scar treatment, and anti-aging formulations.
• Veterinary Medicine: Applied in similar therapeutic areas for companion and performance animals, including wound management and performance recovery.

Basic Information

Item	Details
Product Name	Actovegin
CAS No.	63748-11-8
Molecular Formula	Complex hemodialysate (mixture of organic and inorganic components)
Molecular Weight	N/A (Biological extract with low molecular weight components < 5000 Da)
Synonyms	Deproteinized Calf Blood Hemoderivative; Solcoseryl; Deproteinised Haemoderivative of Calf Blood; Calf Blood Deproteinized Hemolysate; Hemoderivative; Actoveginum; Actovegina; Actovegine; Actovegin (API)
EINECS	Contact for details

Quality Control

Every batch of Actovegin is manufactured under strict quality management systems, ensuring traceability and consistency from raw material sourcing to final release. Our production adheres to current Good Manufacturing Practice (cGMP) guidelines, and the product meets stringent specifications for identity, purity, biological activity, and safety, including tests for absence of pyrogens and specific biological activity. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and safety parameters is provided with each shipment to guarantee compliance with your pharmaceutical-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature, typically between 15°C and 25°C (59°F and 77°F). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Description	Clear, yellowish-brown solution
Identification (IR / HPLC)	Conforms to reference standard
pH	6.5 - 7.5
Assay (Total Solids)	18.0 - 22.0 mg/ml
Protein Content	Not more than 0.05 mg/ml
Molecular Weight Distribution	< 5000 Da
Biological Activity	Conforms to in-vitro test
Bacterial Endotoxins	< 0.5 EU/ml
Sterility	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.